Accounting for linkage disequilibrium in genome-wide association studies: a penalized regression method
نویسندگان
چکیده
منابع مشابه
Accounting for linkage disequilibrium in genome-wide association studies: A penalized regression method.
Penalized regression methods are becoming increasingly popular in genome-wide association studies (GWAS) for identifying genetic markers associated with disease. However, standard penalized methods such as LASSO do not take into account the possible linkage disequilibrium between adjacent markers. We propose a novel penalized approach for GWAS using a dense set of single nucleotide polymorphism...
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ژورنال
عنوان ژورنال: Statistics and Its Interface
سال: 2013
ISSN: 1938-7989,1938-7997
DOI: 10.4310/sii.2013.v6.n1.a10